I have a very special and painful case I need help with, I have tried several different veterinarians with no diagnosis or prognosis so far. It may be a long shot, but I was hoping you could help me shine a light on this.

In April I found an extremely skinny stray cat and took him in. I first thought he was malnourished from lack of food for being in the streets, but 4 months in his case keeps unfolding.

He is likely older than 15 years old, but he’s a happy cat with a lot of energy and mobility. He weighs 3kg but he’s a big cat, you can feel every single bone in his spine, although you can’t see them that easily because he has long hair. He’s completely affectionate, loves to be pet, and asks very politely for attention and food all the time.

All we know about his past is he is neutered, he had some teeth surgically removed and he tested negative for FIV and FeLV.

He had a huge appetite when I first took him in, he would eat 100g of food in one meal and ask for more right after. He would sometimes ‘cough’, it sounded like he was choking on some kind of fluid, it doesn’t happen in sequences, but it happens almost every day until today.

He always drank LOTS of water and produced a lot of urine as well. His feces at the beginning were really solid with some mucus.

After a month, he continued to eat plenty and hadn’t gained any weight, that’s when he started to throw up. It started happening a few days a week, usually after spending several hours without eating he would throw up a clear frothy fluid with no content, and then it progressed to twice every day regardless of when he had eaten.

We suspected it could be diabetes or hyperthyroidism, but the labwork didn’t confirm either, it showed regular kidney function with small liver function alterations.

We then introduced prednisolone (2,5mg/day) and changed his diet from a mix of natural home-cooked protein, hypercaloric wet food, protein supplements, and dry food to exclusively Royal Canin Hypoallergenic while waiting for Royal Canin Gastrointestinal Hydrolyzed Protein to arrive in Brazil, keeping Omega 3 (fish oil) 500mg/a day in his diet.

Vomits went away for a while. He kept drinking lots of water and peeing a lot, but his feces got softer (not liquid).

He had periods where he lost his appetite, which we treated with mirtazapine, he reacted after 6 days.

We performed an ultrasound and discovered that basically all his internal organs were compromised. He has severe alterations everywhere. Still, the best specialists I could find couldn’t tell me what was causing it and offer a course of treatment that didn’t involve opening him up to collect tissues for a biopsy.

I personally think it is absurd that a doctor could look at this frail elderly cat who obviously can’t resist anesthesia without serious risks and say that surgery is the only way to go, all to find out for sure if we’re dealing with a lymphoma or an infection. I’m looking for someone to advise me on the most effective course of action. Of course, I aim to reverse his condition, but I understand that given his age and how advanced it is, it might not be an option.

He is currently at 3kg, eating exclusively Royal Canin Gastrointestinal Hydrolyzed Protein with fish oil, and taking prednisolone every day for a month now. His appetite is healthy, he still drinks a lot, pees a lot, and poops regularly but softer. He eats an average of 5 small meals.
Vomits are back down to a few times a week, usually early in the morning before his first meal, and always a clear liquid. He goes and eats right after throwing up so I get the impression he is not nauseous.
He doesn’t seem to be in pain overall.
He’s not gaining any weight regardless of all my efforts.

That is why I’m giving this a shot and trying to get your attention. I hope you have more resources and knowledge that could help me figure out appropriate next steps to give this little guy the best fighting chances I can.

On this link you’ll find a translation of his bloodwork and ultrasound. I had chat GPT translate it for me so forgive me if there are errors.
Link: https://docs.google.com/document/d/1yqcen-TYzyvfBYU-J4t1tCHola1E2otDGDa1H7V032Y

I appreciate any support you can lend me, his name is Valentim which means brave and strong, and I want him to win this fight.

My 1 year old dog (1/2 lab, 1/4 German shepherd, 1/4 boxer) has a large, perfectly round red bump on her face. I have researched and see potential answers but we are currently out of town and cannot take her to the vet yet. She is very important to me so of course I am concerned, but I would like opinions on whether I should be panicking as much as I am according to the photos I provide. Some articles say cancer, others say histiocytoma.

My cat has been excessively licking herself on her back side, around the tail area and on her paws. So much so that now she has a bald spot on her rear end. This has been going on for a week now, from what I have noticed. I have tried brushing her to look for flea evidence but I have had no luck. She also doesn’t let me see her paws. She has been eating fine and nothing has been different in the home like food wise or litter wise. She occasionally goes out side just onto the deck but not lately due to the heat. What could this be? None of my other cats are showing the same behavior. Do I need to get her seen?

Hello all,
Writing in with an agonizing and drawn out struggle with my cat Petra..

I rescued a feral kitten in 2022 who developed cryptococcosis the following year – confirmed through a biopsy.
She has the cutaneous and nasal form, and while we tried itraconazole for a few months, it did devastating damage to her nose.
Vet switched her to fluconazole 37.5 mg (at that time my cat was just over year old and weighed 3.5 kg) once a day… and the symptom relief was remarkable!
Within a month, her nose was much less inflamed and starting to look “relatively normal” again, and best part was she was no longer having difficulty breathing, no stertor or mouth open.
Her many crusty skin lesions and nodules under the skin cleared up miraculously!

But, the success was short-lived, because a couple of months later she developed a big bulge on her abdomen/side under the skin – which eventually erupted. She had had several of these nodules and lumps, that ulcerated last year but the fluconazole seemed to clear them all up. Until now. I was so disheartened, to say the least.
The crater-like ulcer got infected and our vet (RCVS licensed in UK) decided surgery was the best option.
We did this, and the vet found more ulcers which needed to be removed to patch up the skin. It was a horrific looking surgery aftermath when she came home.

Petra required to wear a cone for 3 weeks after her surgery so she couldn’t touch her healing wound. It got infected anyway, and this increased her “cone suffering” duration.
The impact of many vet visits, surgery, and follow ups while the vet checked if the wound was healing and if the stitches could be removed, was quite an ordeal for Petra.
She gets very stressed and is difficult to put in a carrier. I feel that the stress of cone duration + all the vet trips triggered an inflammatory response in her and her nose started showing signs of the fungus again. Inflammation, distortion and worst of all the stertor was back.

The vet increased her fluconazole dose to 75 mg a day (37.5 mg morning, 37.5 mg evening). This had no noticeable effect and her nose got more inflamed as each day went by. 2 months later and her nose is worse than ever and the tip is so inflamed. With the loss of scent and ability to breathe sufficiently, she’s become reluctant to eat more than half a tin of food a day. Sometimes all she will eat is half a tablespoon and then runs off, upset.

Petra’s vet wants to put her on a maximum dose of 150 mg of fluconazole, daily, before assessing her quality of life and potential euthanasia.
I decided to try homeopathic remedies first, while continuing 75 mg a day of fluconazole) but it doesn’t appear to be helping 3 weeks in.

I’m concerned about continuing vet interventions, because Petra is so stressed by them, and at 150 mg a day she will need to see the vet frequently and likely need blood tests. At 150 mg a day, it’s also a non sustainable chunk of my monthly expenses (taken from diminishing savings), and she is not my only cat or responsibility… this could go on for years..

If she has no positive response (symptoms relief) at 150 mg, the vet is out of ideas other than euthanasia. I live in Bahrain and the options for treating this fungus are very limited.
They have not seen it in over 40 years of vet practice, so this is a first time.

I love Petra and it’s been hell witnessing her struggle to breathe for over a year. That’s what makes me panicky and consider quality of life, if she cannot be cured or brought to a level of management where the fungus doesn’t impede her breathing.

I need advice from a community of animal lovers, vets, who can also understand and take into consideration her temperament and adverse reaction (inflammation) to vet visits.

I was really hoping the homeopathic medicine would help and the practitioner I found has many years of successes working with animals. It’s either the wrong remedy, or just going to take a long time. In the meantime, in my opinion, my cat is suffering and struggling. She takes gasps of air every so often and her mouth is slightly open while she makes a snoring sound as she tries to breathe through her blocked airway. She has lost weight as she eats much less now. She was 4.7 kg in April before her surgery. At the beginning of June she was 4.5 kg and now she is closer to 4 kg.
Also within the last 2 months, her eyes have gotten affected by the nodules. One above her right eye, under the skin and affecting the bone. The other is in her left lower eyelid.
During this whole ordeal, her right lymph node under her jaw has been the size of a golf ball.. and the left one also swelled up a few months later. But that side seems to have gone down.

Any help or advice on what to do.. would be very much appreciated.

Pics from most recent (today June 3rd 2024) to last year before fluconazole and way before, late 2022, when she was a kitten.

Hello! I have a 14 month Bernese Mountain dog who has been limping for quite a while now. He started off with lameness shifting over all 4 legs, but now he is just lame in the front left. It’s constant and gets worse when he runs about and will hold his leg up. He doesn’t whine and it doesn’t prevent him from activities. I’ve reduced his walks to lead walks, and even reduced his walking to see if that helps but it hasn’t made a difference. He’s had an x ray of all four limbs, checking for hip and elbow dysplasia and his legs and joint all look good with no issues… We’ve been advised this is growing pains, which we suspected and heard is quite common in young large breed dogs. However, this lameness has been going on for a more than a couple of weeks and no sign of it getting better. Checked his paw pads and in between to see if there is anything stuck. No heat or swelling or cuts anywhere. Anyone else experienced prolonged lameness with no obvious source? Or any advise as to how I could identify a source? I’m just concerned something’s been missed as it’s been going on for a long time.

My dog recently had surgery and I gave her her antibiotic last night while my wife wasn’t home and she woke up this morning and have her another dose because she didn’t realize I had given it last night. It’s 200mg of CEFPODOXIME – proxetil. Is there any cause for concern?

I have a 6 year old, female Doberman mix (we rescued her and not sure her exact breed-she is smaller than most Doberman-she is around 44 lbs. About a month ago, she started having accidents in the house, constant urination, and dribbling stream when she actually pees. I thought she probably had a UTI and took her to the vet. They assumed as well she probably had a UTI and gave me a prescription. After ten days on prescription, no change. I went back to vet and told her there had been no change. They started her on Proin. She has been taking this for about 2.5 weeks and there has been no change. When I take her out , she pees about 4 times in a dribble.

They have done blood tests, urinalysis, and x ray. Even after using bathroom twice, her bladder still had urine in it. They are going to send it to a specialist, but we are already about $800 in and no answers. I feel so bad for my girl, because she is embarrassed when she has an accident inside. Any help would be great!

My dog is predisposed to have reactions to ingredients in every heartworm medication. I have received no definitive answer from my vet as to what to do except to basically play Russian Roulette which I’m not really willing to do. I would like to know if you have any advice on how to herbally treat heartworm without using conventional treatment. He is a husky, German Shepherd, wolf mix he has been DNA tested and he is 20 months old. Any information that you could provide would be helpful. My name is James Dalton and if you need to contact me my number is 864-906-4305. Thank you

My 18 month old pit bull American bulldog mix , has a spot on his upper paw that’s raised. He licks the spot sometimes. Should I be concerned ?

Help Saving Ava, our 7 yr old chihuahua! She is currently at our vet in oxygen, fighting for her life, her trachea is 100% collapsed. She also suffers from epilepsy and is on 3 different meds to control her seizures. The specialty vets want at least $10k to just get in the door. We are fairly close to you, is there anyway you or someone you know can perform this surgery??? They have her on numerous injectable medications to try to bring the inflammation down including several antibiotics, we went to visit her today but if we take her out of the oxygen even for a minute or two her tongue starts to turn blue. Please help if you can, we are desperate at this point! She’s only 7 ????