Question
Profile Image
Maryam | 5 months ago
Hello All, Writing In With An Agonizing And Drawn Out Struggle With My Cat Petra.. I …

Hello all,
Writing in with an agonizing and drawn out struggle with my cat Petra..

I rescued a feral kitten in 2022 who developed cryptococcosis the following year – confirmed through a biopsy.
She has the cutaneous and nasal form, and while we tried itraconazole for a few months, it did devastating damage to her nose.
Vet switched her to fluconazole 37.5 mg (at that time my cat was just over year old and weighed 3.5 kg) once a day… and the symptom relief was remarkable!
Within a month, her nose was much less inflamed and starting to look “relatively normal” again, and best part was she was no longer having difficulty breathing, no stertor or mouth open.
Her many crusty skin lesions and nodules under the skin cleared up miraculously!

But, the success was short-lived, because a couple of months later she developed a big bulge on her abdomen/side under the skin – which eventually erupted. She had had several of these nodules and lumps, that ulcerated last year but the fluconazole seemed to clear them all up. Until now. I was so disheartened, to say the least.
The crater-like ulcer got infected and our vet (RCVS licensed in UK) decided surgery was the best option.
We did this, and the vet found more ulcers which needed to be removed to patch up the skin. It was a horrific looking surgery aftermath when she came home.

Petra required to wear a cone for 3 weeks after her surgery so she couldn’t touch her healing wound. It got infected anyway, and this increased her “cone suffering” duration.
The impact of many vet visits, surgery, and follow ups while the vet checked if the wound was healing and if the stitches could be removed, was quite an ordeal for Petra.
She gets very stressed and is difficult to put in a carrier. I feel that the stress of cone duration + all the vet trips triggered an inflammatory response in her and her nose started showing signs of the fungus again. Inflammation, distortion and worst of all the stertor was back.

The vet increased her fluconazole dose to 75 mg a day (37.5 mg morning, 37.5 mg evening). This had no noticeable effect and her nose got more inflamed as each day went by. 2 months later and her nose is worse than ever and the tip is so inflamed. With the loss of scent and ability to breathe sufficiently, she’s become reluctant to eat more than half a tin of food a day. Sometimes all she will eat is half a tablespoon and then runs off, upset.

Petra’s vet wants to put her on a maximum dose of 150 mg of fluconazole, daily, before assessing her quality of life and potential euthanasia.
I decided to try homeopathic remedies first, while continuing 75 mg a day of fluconazole) but it doesn’t appear to be helping 3 weeks in.

I’m concerned about continuing vet interventions, because Petra is so stressed by them, and at 150 mg a day she will need to see the vet frequently and likely need blood tests. At 150 mg a day, it’s also a non sustainable chunk of my monthly expenses (taken from diminishing savings), and she is not my only cat or responsibility… this could go on for years..

If she has no positive response (symptoms relief) at 150 mg, the vet is out of ideas other than euthanasia. I live in Bahrain and the options for treating this fungus are very limited.
They have not seen it in over 40 years of vet practice, so this is a first time.

I love Petra and it’s been hell witnessing her struggle to breathe for over a year. That’s what makes me panicky and consider quality of life, if she cannot be cured or brought to a level of management where the fungus doesn’t impede her breathing.

I need advice from a community of animal lovers, vets, who can also understand and take into consideration her temperament and adverse reaction (inflammation) to vet visits.

I was really hoping the homeopathic medicine would help and the practitioner I found has many years of successes working with animals. It’s either the wrong remedy, or just going to take a long time. In the meantime, in my opinion, my cat is suffering and struggling. She takes gasps of air every so often and her mouth is slightly open while she makes a snoring sound as she tries to breathe through her blocked airway. She has lost weight as she eats much less now. She was 4.7 kg in April before her surgery. At the beginning of June she was 4.5 kg and now she is closer to 4 kg.
Also within the last 2 months, her eyes have gotten affected by the nodules. One above her right eye, under the skin and affecting the bone. The other is in her left lower eyelid.
During this whole ordeal, her right lymph node under her jaw has been the size of a golf ball.. and the left one also swelled up a few months later. But that side seems to have gone down.

Any help or advice on what to do.. would be very much appreciated.

Pics from most recent (today June 3rd 2024) to last year before fluconazole and way before, late 2022, when she was a kitten.

5 Responses

Comments

  1. Krista Magnifico

    Hello,
    I am so sorry to hear of your frustration over your cats case.
    I am not able to give much advice on this case with specific details to treatment but I will add that I think seeing a feline practitioner (someone who just sees cats) and see if they can help.
    I am sorry but I cannot advise a homeopathic vet on this case, it is too far advanced.

    I wish you the best of luck

    1. Maryam Post author

      Thank you, Dr. Magnifico,
      I have agreed to up her dose to 150 mg of fluconazole and it’s been a week with no improvements so far – except I noticed her drinking more water. Living on a small island, we don’t have any feline only vets, every vet here sees both cats and dogs. I really don’t want to elect euthanasia (which the vet said is an option) and the other end of the spectrum is my fear that she will suffocate eventually. It’s been so painful watching this unfold. Thank you for responding, about homeopathy. It is an added cost and couriers to get the medicine in. I have been desperate.

  2. Shiria

    Hello,
    I’m so sorry to hear that your cat is so unwell. I’ve luckily never seen ryptococcosis, but if it is treated with itraconazole or fluconazole, maybe ketaconazole is an option to try, too?
    Thank you for trying so much for your cat and not giving up on her. You are both amazing.
    Shiria

    1. Maryam Post author

      Hello Shiria, thank you for your kind comment. Petra is amazingly resilient.
      Animals take on suffering without complaint so I don’t know if I’m doing the right thing at this point, if she won’t get better. I’ve read about ketoconazole but it seems like the least helpful of the two azoles for this condition, and it seems like it has more adverse effects too. I will look into it, though, I don’t know if I’m doing the right thing for her as she struggles to breathe and trials take time. It hurts to think of putting her down and it hurts to see her suffering without knowing what will help, or if anything will. At a certain point I ask if it’s selfish to keep her alive & suffering in the hopes something will help, over a year on.

  3. Maryam Post author

    Hello. An update for anyone in the future researching on behalf of their pet who develops this fungus.
    A cure is possible, some cats respond very well to anti-fungal meds. My Petra did not. Initially, her nose cleared up very well and she could breathe much better, but the fungus returned with a vengeance a few months later.

    She has been on Fluconazole for 11 months total:
    (37.5mg – 75mg), and on 150mg for 3 months. 2 months into the higher dose, I found her with anisocoria (one pupil very dilated). It went away and came back over two days. One of her eyes is droopy (Horner’s syndrome). Yesterday I found blood smeared on her paw and couldn’t find a wound.

    I took her to the vet, who opened her mouth and discovered the fungal growths are pushing through her soft palate (roof of mouth) and causing anatomical separation. Her nose is swelling up considerably and distorting again. It began regressing 6 months ago but was relatively stable, but now it’s increasing in size and doubling almost overnight. She has lost 1 kilo. The vet has recommended euthanasia, unequivocally. Petra is struggling to get air in, and while we hoped for a cure (with medication) that is not happening. It’s cruel to continue with no hope of quality of life and only more suffering, and the outcome if left would be suffocation.

    We have decided to let my sweet girl go, while she is still mobile, eating, before she suffocates to death.

    It’s been so traumatic, to witness this and I want to send good vibes to anyone in the future who is struggling with the same disease (mainly the nose – which causes so much suffering).

Question
Profile Image
Naomi | 5 months ago
Hello! I Have A 14 Month Bernese Mountain Dog Who Has Been Limping For Quite A While …

Hello! I have a 14 month Bernese Mountain dog who has been limping for quite a while now. He started off with lameness shifting over all 4 legs, but now he is just lame in the front left. It’s constant and gets worse when he runs about and will hold his leg up. He doesn’t whine and it doesn’t prevent him from activities. I’ve reduced his walks to lead walks, and even reduced his walking to see if that helps but it hasn’t made a difference. He’s had an x ray of all four limbs, checking for hip and elbow dysplasia and his legs and joint all look good with no issues… We’ve been advised this is growing pains, which we suspected and heard is quite common in young large breed dogs. However, this lameness has been going on for a more than a couple of weeks and no sign of it getting better. Checked his paw pads and in between to see if there is anything stuck. No heat or swelling or cuts anywhere. Anyone else experienced prolonged lameness with no obvious source? Or any advise as to how I could identify a source? I’m just concerned something’s been missed as it’s been going on for a long time.

1 Response

Comments

  1. Laura

    Not a vet, but someone who was heavily invested in Doberman breed education. We see this a lot in Dobermans fed puppy diets (not large breed puppy_. What are you feeding, and is it an adult or All Life Stages food? Have you consulted an ortho vet?

Question
Profile Image
Justin | 5 months ago
My Dog Recently Had Surgery And I Gave Her Her Antibiotic Last Night While My Wife …

My dog recently had surgery and I gave her her antibiotic last night while my wife wasn’t home and she woke up this morning and have her another dose because she didn’t realize I had given it last night. It’s 200mg of CEFPODOXIME – proxetil. Is there any cause for concern?

1 Response

Comments

Question
Profile Image
Jen | 5 months ago
I Have A 6 Year Old, Female Doberman Mix (we Rescued Her And Not Sure Her Exact …

I have a 6 year old, female Doberman mix (we rescued her and not sure her exact breed-she is smaller than most Doberman-she is around 44 lbs. About a month ago, she started having accidents in the house, constant urination, and dribbling stream when she actually pees. I thought she probably had a UTI and took her to the vet. They assumed as well she probably had a UTI and gave me a prescription. After ten days on prescription, no change. I went back to vet and told her there had been no change. They started her on Proin. She has been taking this for about 2.5 weeks and there has been no change. When I take her out , she pees about 4 times in a dribble.

They have done blood tests, urinalysis, and x ray. Even after using bathroom twice, her bladder still had urine in it. They are going to send it to a specialist, but we are already about $800 in and no answers. I feel so bad for my girl, because she is embarrassed when she has an accident inside. Any help would be great!

1 Response

Comments

  1. Krista Magnifico

    Hello,
    I think that there are really only two good options. See if you can find another general practitioner to review your pup with an examination and a review of what you have done already or take the referral for the best chance at getting your diagnosis.
    In some cases your original vet can call for a consultation with the veterinarians who provide the diagnostics. You can ask about this. It is free and often gives them access to a specialist without the cost.

Question
Profile Image
James | 6 months ago
My Dog Is Predisposed To Have Reactions To Ingredients In Every Heartworm Medication. I Have Received …

My dog is predisposed to have reactions to ingredients in every heartworm medication. I have received no definitive answer from my vet as to what to do except to basically play Russian Roulette which I’m not really willing to do. I would like to know if you have any advice on how to herbally treat heartworm without using conventional treatment. He is a husky, German Shepherd, wolf mix he has been DNA tested and he is 20 months old. Any information that you could provide would be helpful. My name is James Dalton and if you need to contact me my number is 864-906-4305. Thank you

1 Response

Comments

Question
Profile Image
Brittany | 7 months ago
My 18 Month Old Pit Bull American Bulldog Mix , Has A Spot On His Upper Paw That’…

My 18 month old pit bull American bulldog mix , has a spot on his upper paw that’s raised. He licks the spot sometimes. Should I be concerned ?

3 Responses

Comments

  1. Laura

    Licking the spot usually means it’s irritating in some way. I’d absolutely get him to the vet.

  2. Krista Magnifico

    Hello,
    It is not possible to diagnose any lesion based on a picture. A diagnosis of a mass is only made after a tissue sample is analyzed by a pathologist. I would see your vet and ask them to give their best guess as to what it is and I would also ask them about the possibility of it being a histiocytoma. Even this is only diagnosed after a biopsy. Let us know what they say.

    1. Brittany Post author

      His appointment is next Wednesday, my heart is breaking in the meantime

Question
Profile Image
April | 7 months ago
Help Saving Ava, Our 7 Yr Old Chihuahua! She Is Currently At Our Vet In Oxygen, Fighting …

Help Saving Ava, our 7 yr old chihuahua! She is currently at our vet in oxygen, fighting for her life, her trachea is 100% collapsed. She also suffers from epilepsy and is on 3 different meds to control her seizures. The specialty vets want at least $10k to just get in the door. We are fairly close to you, is there anyway you or someone you know can perform this surgery??? They have her on numerous injectable medications to try to bring the inflammation down including several antibiotics, we went to visit her today but if we take her out of the oxygen even for a minute or two her tongue starts to turn blue. Please help if you can, we are desperate at this point! She’s only 7 ????

0 Responses
Question
Profile Image
Marie | 7 months ago
Has Anyone Had A Dog Die Of Congestive Heart Failure After Being On A No Grain …

Has anyone had a dog die of congestive heart failure after being on a no grain diet? My American Bulldog had bad allergies to grains and anything w feathers so I kept her diet limited ingredient grain free. She died suddenly of congestive heart failure and I would like to know what to do if your dog needs to be on a restricted diet how do you keep them safe from hear failure. She was only 8 and it broke my heart to lose her. She collapsed right in front of me

9 Responses

Comments

  1. Krista Magnifico

    Hello,
    The answer for this comes in a few parts.
    First, yes, I suspect I have had some patients die from heart failure secondary to grain free diets. These were confirmed as suspected by the cardiologist who saw them after me. So. Yes. I am concerned that grain free contributes detrimentally to heart disease and death.

    Second was heart disease confirmed by your vet? Or a cardiologist? I see far more bulldogs dying from brachycephalic syndrome disease than anything else. By a lot. I had three die this summer from inability to breathe after getting too hot or too overexerted. Unless your dog was diagnosed with a heart condition I suspect it was the head and face that caused the issue and not the heart. That’s just been my experience over 20 years in practice.

    1. Marie Post author

      Is there a way to see Racheal’s syndrome disease coming? I never let her over exert or get too hot. She’s my baby and I guard her health and well being ferociously. I have been called over protective but I want her to be with me as long as possible.

      What are your thoughts on Raw and freeze dried raw diets.? It makes sense to me to feed as close to nature as possible but the diets also scare me – bacterial infections etc.

  2. Laura

    A friend’s golden lost his life to a cardiac event after several years on a grain free diet, confirmed by necropsy that he had a heart attack. The problem with grain-free diets is the substitution of legumes as fillers – this seems to be the contributing factor for dietary DCM. Did you have a necropsy done to verify it was the heart?

    I’m so very sorry. Assuming your dog had dietary DCM, DCM is the absolute worst. We lost our Doberman in the same way, to sudden death, but in her case it’s endemic in the breed and she was diagnosed a little over a year prior. If it’s any consolation, the arrhythmic form of DCM – also called sudden death – does not allow the dog to suffer. It’s over like someone flipped a light switch. I know that’s the form I preferred for my dog – it SUCKED for us, but it was an easy departure for her, and that’s what matters most.

    I would start researching raw, if you have a dog in need of a very restrictive diet that cannot easily be satisfied by mass produced options. Do a L O T of research into raw, as it’s more complicated than feeding a kibble diet.

    1. Marie Post author

      It’s so heartbreaking to lose our fur babies so suddenly. Well anytime to be honest but it’s worse when you can’t prepare. I am sorry for your loss.

      I have been researching raw and freeze dried raw and the decision making is daunting.

  3. Marie Post author

    Many thanks to you both for the responses. My Bunny did die from congestive heart failure confirmed post mortem. It was so chocking when she died. I came in the door, she bounced across the room to greet me and collapsed at my feet. The emergency clinic could do nothing to save her.

    I now have a second American Bulldog and am worried for her as she has allergies as well. I am doing a partial limited ingredient diet and looking at raw or freeze dried raw. But it’s a lot to sift through so it’s a process. I don’t believe Peanuts allergies are food based but environmental. Apoquel sparingly and Cytopoint are keeping things at bay.

    What are your thoughts on giving a taurine supplement to counter the effects of the no grain diets?

    1. Laura

      I would do trials of various proteins to verify the allergies are, in fact, environmental, and then feed a limited ingredient kibble based on that. There are several on the market if you’re in the US. I know someone whose greyhound couldn’t do fish or chicken and did exceedingly well on Natural Balance.

  4. Marie Post author

    Thanks I did 6 months worth of food trial as well as feeding a hypoallergenic Rx diet. It did not change her itching/allergies. Seasonally they seem to be worse and being outside makes them worse. So indoors it is, Apoquel and cytopoint. For now.

    1. Laura

      Ah, sounds environmental for sure. I’d just feed a decent grain inclusive food.

Question
Profile Image
Vanessa | 7 months ago
Hello. I Got A Puppy A Few Weeks Ago And Was Told That He Was Six …

Hello.

I got a puppy a few weeks ago and was told that he was six weeks old. I started him on stage two puppy formula and over the next three weeks, transitioned him to dry puppy food. For the last two weeks, he still eating a normal amount of food drinking a normal amount of water super energetic as a normal puppy would be, but he has persistent diarrhea. I assumed it was from changing his food’s.

I had set up an appointment with Vetco for this past Tuesday for his first visit/wellness checkup and his first set of shots. They called me Monday night letting me know they have to reschedule me for this upcoming Tuesday (4/30). I wanted to have them look at Artemis’ anal gland/sacs because I feel like they are not being released while he is having really bad diarrhea. Within the last four days, there has been drops of blood in his stool from him constantly pushing and nothing coming out. He will use the restroom and then he will stain himself to the point that his rectum or colon is popping out. I explained all this to the vet Monday when it was starting and I told them that I have been giving him homemade sweet potato cakes, and carrots to try to build up his fiber intake to help him fight the diarrhea. I also told them I changed him from Purina puppy chow to pedigree puppy chow, and I even tried giving him rice mixed with his puppy food, but he rejects it like the plague. They told me if there’s any blood to get him to urgent care, but I don’t know if I can afford the bill for urgent care and he hasn’t shown any signs of being in distress.

He’s still eating healthy, drinking and being extremely active as a nine week puppy would. I don’t know how to get the diarrhea to stop and I don’t know how to get him to stop pushing when there’s nothing to push out. When he does poop, it is soft, but not liquidy. This last batch of sweet potato cakes I made I have mixed them with the white rice and he can’t seem to get enough of them, but it isn’t making a big difference as far as helping his feces harden to the point where they will help him release his sacs.

How do I get him to stop trying to poop every few minutes there’s nothing there?

1 Response

Comments

  1. Krista Magnifico

    Hello,

    We our puppy needs to see a vet asap. You also need to have a fecal sample submitted for intestinal parasites. Start there. Please do not buy an otc dewormer. See a vet. And do a fecal.
    I always recommend that a vet see a new pet within 3 days.

Question
Profile Image
Julie | 8 months ago
My 1.5 Year Old High Energy Goldendoodle Had Her Front Leg Amputated Almost 3 Weeks Ago Due To …

My 1.5 year old high energy goldendoodle had her front leg amputated almost 3 weeks ago due to a brachial plexus injury. She developed a seroma that was confirmed by the surgeon and she said warm compresses and rest. I have read that these can take weeks to go away and the only way to keep my girl quiet is trazadone, otherwise she wants to run around and play (and due to the amputation, she hops). Is there anything else i can do to speed up the absorption of the seroma?

1 Response

Comments

  1. Krista Magnifico

    Hello,

    I don’t know of anything. I feel that the more you do to annoy or fuss with it the more delayed it gets in being reabsorbed.