A question for Krista Magnifico:

Hello! Hoping to get some advice on recommended next steps for my cat, Sammie, who is being evaluated for IBD vs. small cell lymphoma.

Sammie is 17 years old and is overall quite healthy! Throughout the time I’ve had her, she’s had a history of vomiting a ~once per week or two (sometimes more frequently). Vomit is usually clear, foamy. No other GI issues or health issues otherwise. She is active and energetic, and has not had any health issues until ~1 month ago when I noticed she stopped eating as much as she previously did. She stopped eating her dry food altogether, and seemed to become quite picky with her wet food. I initially thought her teeth may be bothering her because of the avoidance of dry food, so I brought her to the vet.

Vet found that she had lost a couple of pounds, unintentionally. Based on presenting symptoms, vet thought she might have a GI pathology so ordered an abdominal U/S:

Ultrasound, Abdominal Study Outcome:
Kidneys: overall normal size but mild reduction in detail and small mineral foci. Trace pylectasia noted w/out ureteral disension.
GI: Avg SI thickness normal. Mild corrugation is noted in some regions and some ileus (luminal fluid distension up to 4 mm w/ reduced
peristalsis) noted w/out obstruction. No discrete abnormalities appreciated throughout the small intestines.
Caudal abdominal nodes are prominent to mildly enlarged and rounded w/ smooth texture. One irregular cystic structure noted near right
kidney. The mesentery around the ileus segments is mildly hyperechoic.
A:
Intestines most consistent w/ enteritis
Nodes: r/o reactive vs other
Cystic strucure: r/o benign mesenteric vs inflamed node
Kidneys have evidence of chronic disease.

Here are her prior labs:
PRIOR LABS:

7/15/24: Wt loss 0.28 lb; PCV: 40/7.6; Chem18: BUN 41, creat 1.7, K+ 4.3, phos 4.2
U/A: USG 1.019, pH 6.0, rare wbc/rbc; no bact/cryst; cobalamin: 437; folate: 11.2

2/13/24: Wt loss 0.8 lb; CBCcomp: hct 44, diff wnl (clots in sample; rec. resubmit)
Chem25: BUN 40, creat 1.3; T4: 2.8; SDMA <10
U/A: USG 1.025, pH 6.0, rare wbc, no rbc/bact/cryst, rare fine gran casts.

1/19/23: Wt loss 0.4 lb; CBC: (hct 40, diff wnl); Chem25: (BUN 32, creat 1.3)
T4: 1.8; U/A: USG 1.051, pH 6.5, 1+ prot, rare wbc, no rbc/bact/cryst

11/19/21: CBC: (hct 46, diff wnl); Chem: (BUN 34, creat 1.5); T4. 1.9; DGGR lipase 9
U/A: USG 1.053, pH 7.5, rare amorph. crystals, no wbc, no rbc

6/17/22 Wt loss 0.16 (as desired); USG 1.040; SDMA: 11

Most recent A&P:
A:
1) Intestines most consistent w/ enteritis (IBD vs SCLSA); ileus likely cause of decreased appetite.
2) Nodes: r/o reactive vs other
3) Cystic strucure: r/o benign mesenteric vs inflamed node
4) Kidneys have evidence of chronic disease ; in keeping w/ previous lab findings.
P:
1) Rx: metoclopramide 5 mg: 1/4 tab po every 8-12 hrs.
2) Continue vit B12 as Rxed.
3) picked up Mirataz but hasn't started it yet. Rec. give. metoclopramide for 2-3 days and then if not improved appt, start Mirataz.
4) to consider presumptive pred tx vs ex-lap for biopsies.

Sammie is seeming to eat better with the metoclopramide.

My question:
Is pusuing an ex-lap for biopsy recommended vs. empiric tx for IBD with steroids vs. empiric tx for SCL with steroids + chlorambucil.

Thank you!!!

my dog ( 1 1/2 year old small mix terrier) is a sweet guy when it comes to humans and dogs he is familiar with. sadly, he has picked up aggressive behaviors from my brothers large dogs. He will growl at people he is not familiar with on the street and when they enter the home. he will growl at outside noises and also at other unfamiliar dogs. he doesn’t bite people he just growls and when they try to pet him he runs away and gets shy. minutes will pass and he will warm up to people. he does fine at the dog park, when a dog approaches he smells the dog and runs away( which makes sense, he is a small dog) i’m more concerned when we go on walks. i’m looking for advice and tips i can do to help me and my dog work on his excessive growling. i would love to be able to go on a walk with him and be able to pass people without him growling and he can just keep walking.

I have adopted a dog from the pound about 4 or 3 moths ago, he is a very good dog but when someone enters my room, my dog starts growling and he won’t stop. The behaviour has gotten worse when my fathers partner hit him with a leash with a metal spring on it, now whenever he hears someone walking outside of my room (going upstairs or to the bathroom) he immediately starts growling, his growling got more loud and now when someone passes him, he’s scared and walks away. Another thing is when I leave the house, he starts howling and it’s annoying my father he wants me to sell him but I still believe there is something to help my dog. He is a sheepdog collie mix and 2 years old, he is a very good dog and I presume his previous owners must have been abusing him since he’s scared of everything. Is there a way to teach him not to do it?

I need your advise regarding my 11 months old Persian male cat. the problem is that my cat wants to go out for mating and if we do not let him go out he sprays and pees in the house which causes a very bad odor in the house. Now that we have let him out on his own he has started to spray around outside and you can smell the odor as soon as you enter through gate.
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Thirdly, there is a stray cat outside which is on heat all he does is that he sits beside her all day long and if we bring him inside the female cat starts to cry which make him go crazy to go outside.
Finally, I want to ask you about getting my cat neutered. The pros and cons of getting the cat neutered. I have heard from someone that the cat’s personality changes and we have to take care of him more because there will be a wound after his operation and all the people in our house go to work. Hence, there can be a problem in taking care of him 24/7.