I have a 3 and a half year old GSD with HYPOthyroidism. I’m curious if anyone else has dealt with this disease in itself. So to begin, when she was about a year old I started noticing redness on her stomach. The vet I was currently with kept telling me she had ringworm and providing me with medicated shampoo and treating her with ketoconazole. It always seemed to clear up but would come right back soon after. So I searched and found another vet and he did all the testing and blood work and diagnosed her with HYPOthyroidism. She has kept a chronic skin infection which he diagnosed as a type of yeast infection due to the fluctuation of thyroid levels. She has been on levothyroxine for a year now. We have adjusted her dosage 3 times and each time she seems to do well for a month or so and then it seems to “level out” and her skin flare up comes back full force. It seems to get better and lightens up and starts to pink up and then goes right back to the hair loss and crusty on her stomach and under her legs/pits. I continue to do the medicated baths as told but it’s getting frustrating. I’m in the vet’s office every couple months it seems and spending hundreds each visit for the same thing with no resolve. Dont get me wrong I will do whatever it takes to help her but somethings gotta give. I’m just curious if anyone else has seen/heard or has dealt with hypothyroidism and the chronic skin infection. Have u found anything that helps or resolves it? What is your experience? Also she keeps bad ear infections (also tested and diagnosed as a type of yeast) daily flushes and drops in her ears as well. Still not seeming to get any better.

I feel so helpless and quite frankly I’m getting discouraged. I love the vet she sees now, he is a million times better than the one she seen previously.

Does it ever get better?

The pic is an older one, shes alot better now but still has the hairloss and discoloration over the better part of her stomach and under her legs. Just not as dark or as much.

Question for Dr. Krista; sorry, complicated question(?)

First, to review for benefit of others reading this question:

Patient: Cookie
Rottweiler, spayed female, 2 years old

Presented with lethargy, anorexia, vomiting and diarrhea (threw up only twice and one time diarrhea, then taken to vet, given antiemetics and antibiotics; diagnosed with pancreatitis; getting better since – this was Monday)

During exam foreign material found in stool (grain and corn; we think she got into the horse feed) painful cranial abdomen, low and large bowel diarrhea, enlarged submandibular nodes – this part worries me because these were temporarily enlarged not long ago; resolved quickly, though)

As I’m reviewing the blood results, there are things I could understand as being consistent with digestive distress/pancreatitis but some which are concerning me, namely the globulin and lymphocyte levels, even though they are not extremely low but low nonetheless.

Beside the cPL which is clear in its meaning, the free T4 is low – I assume this is what is meant by not testing for hypothyroidism in ill animals, because the thyroid hormones would be low with any disease process? Is that correct?

I would figure that the ALT/unhappy liver enzymes would also be consistent with such insult to the body, is that correct? And I imagine same would apply to bilirubin in a situation of digestive upset?

The values that concern me are the globulin and the lymphocytes, particularly together with the "easily aggravated" sub mandibular lymph nodes in the mix, particularly as it seems that lymphopenia would be present with both CPV and lymphoma … ? I’d assume that a) Cookie was recently vaccinated for CPV and is improving too rapidly to think CPV? Lymphoma has been on my afraid mind since the first time they were found enlarged.

It also says, though, that lymphopenia could be a result of underactive glands (the source doesn’t say which ones) so would that perhaps have to do with the lowered thyroid function during the digestive distress?

Didn’t find much on low globulins, other than immunodeficiency types of situations, which doesn’t seem to apply. What is the "life-span" of a globulin, and if short, would the low globulins have to do with the unhappy liver?

Can you, please confirm about the free T4 and talk to me about the globulin and more importantly the lymphocytes?

Blood results attached.