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Maryam | 5 months ago
Hello All, Writing In With An Agonizing And Drawn Out Struggle With My Cat Petra.. I …

Hello all,
Writing in with an agonizing and drawn out struggle with my cat Petra..

I rescued a feral kitten in 2022 who developed cryptococcosis the following year – confirmed through a biopsy.
She has the cutaneous and nasal form, and while we tried itraconazole for a few months, it did devastating damage to her nose.
Vet switched her to fluconazole 37.5 mg (at that time my cat was just over year old and weighed 3.5 kg) once a day… and the symptom relief was remarkable!
Within a month, her nose was much less inflamed and starting to look “relatively normal” again, and best part was she was no longer having difficulty breathing, no stertor or mouth open.
Her many crusty skin lesions and nodules under the skin cleared up miraculously!

But, the success was short-lived, because a couple of months later she developed a big bulge on her abdomen/side under the skin – which eventually erupted. She had had several of these nodules and lumps, that ulcerated last year but the fluconazole seemed to clear them all up. Until now. I was so disheartened, to say the least.
The crater-like ulcer got infected and our vet (RCVS licensed in UK) decided surgery was the best option.
We did this, and the vet found more ulcers which needed to be removed to patch up the skin. It was a horrific looking surgery aftermath when she came home.

Petra required to wear a cone for 3 weeks after her surgery so she couldn’t touch her healing wound. It got infected anyway, and this increased her “cone suffering” duration.
The impact of many vet visits, surgery, and follow ups while the vet checked if the wound was healing and if the stitches could be removed, was quite an ordeal for Petra.
She gets very stressed and is difficult to put in a carrier. I feel that the stress of cone duration + all the vet trips triggered an inflammatory response in her and her nose started showing signs of the fungus again. Inflammation, distortion and worst of all the stertor was back.

The vet increased her fluconazole dose to 75 mg a day (37.5 mg morning, 37.5 mg evening). This had no noticeable effect and her nose got more inflamed as each day went by. 2 months later and her nose is worse than ever and the tip is so inflamed. With the loss of scent and ability to breathe sufficiently, she’s become reluctant to eat more than half a tin of food a day. Sometimes all she will eat is half a tablespoon and then runs off, upset.

Petra’s vet wants to put her on a maximum dose of 150 mg of fluconazole, daily, before assessing her quality of life and potential euthanasia.
I decided to try homeopathic remedies first, while continuing 75 mg a day of fluconazole) but it doesn’t appear to be helping 3 weeks in.

I’m concerned about continuing vet interventions, because Petra is so stressed by them, and at 150 mg a day she will need to see the vet frequently and likely need blood tests. At 150 mg a day, it’s also a non sustainable chunk of my monthly expenses (taken from diminishing savings), and she is not my only cat or responsibility… this could go on for years..

If she has no positive response (symptoms relief) at 150 mg, the vet is out of ideas other than euthanasia. I live in Bahrain and the options for treating this fungus are very limited.
They have not seen it in over 40 years of vet practice, so this is a first time.

I love Petra and it’s been hell witnessing her struggle to breathe for over a year. That’s what makes me panicky and consider quality of life, if she cannot be cured or brought to a level of management where the fungus doesn’t impede her breathing.

I need advice from a community of animal lovers, vets, who can also understand and take into consideration her temperament and adverse reaction (inflammation) to vet visits.

I was really hoping the homeopathic medicine would help and the practitioner I found has many years of successes working with animals. It’s either the wrong remedy, or just going to take a long time. In the meantime, in my opinion, my cat is suffering and struggling. She takes gasps of air every so often and her mouth is slightly open while she makes a snoring sound as she tries to breathe through her blocked airway. She has lost weight as she eats much less now. She was 4.7 kg in April before her surgery. At the beginning of June she was 4.5 kg and now she is closer to 4 kg.
Also within the last 2 months, her eyes have gotten affected by the nodules. One above her right eye, under the skin and affecting the bone. The other is in her left lower eyelid.
During this whole ordeal, her right lymph node under her jaw has been the size of a golf ball.. and the left one also swelled up a few months later. But that side seems to have gone down.

Any help or advice on what to do.. would be very much appreciated.

Pics from most recent (today June 3rd 2024) to last year before fluconazole and way before, late 2022, when she was a kitten.

5 Responses

Comments

  1. Krista Magnifico

    Hello,
    I am so sorry to hear of your frustration over your cats case.
    I am not able to give much advice on this case with specific details to treatment but I will add that I think seeing a feline practitioner (someone who just sees cats) and see if they can help.
    I am sorry but I cannot advise a homeopathic vet on this case, it is too far advanced.

    I wish you the best of luck

    1. Maryam Post author

      Thank you, Dr. Magnifico,
      I have agreed to up her dose to 150 mg of fluconazole and it’s been a week with no improvements so far – except I noticed her drinking more water. Living on a small island, we don’t have any feline only vets, every vet here sees both cats and dogs. I really don’t want to elect euthanasia (which the vet said is an option) and the other end of the spectrum is my fear that she will suffocate eventually. It’s been so painful watching this unfold. Thank you for responding, about homeopathy. It is an added cost and couriers to get the medicine in. I have been desperate.

  2. Shiria

    Hello,
    I’m so sorry to hear that your cat is so unwell. I’ve luckily never seen ryptococcosis, but if it is treated with itraconazole or fluconazole, maybe ketaconazole is an option to try, too?
    Thank you for trying so much for your cat and not giving up on her. You are both amazing.
    Shiria

    1. Maryam Post author

      Hello Shiria, thank you for your kind comment. Petra is amazingly resilient.
      Animals take on suffering without complaint so I don’t know if I’m doing the right thing at this point, if she won’t get better. I’ve read about ketoconazole but it seems like the least helpful of the two azoles for this condition, and it seems like it has more adverse effects too. I will look into it, though, I don’t know if I’m doing the right thing for her as she struggles to breathe and trials take time. It hurts to think of putting her down and it hurts to see her suffering without knowing what will help, or if anything will. At a certain point I ask if it’s selfish to keep her alive & suffering in the hopes something will help, over a year on.

  3. Maryam Post author

    Hello. An update for anyone in the future researching on behalf of their pet who develops this fungus.
    A cure is possible, some cats respond very well to anti-fungal meds. My Petra did not. Initially, her nose cleared up very well and she could breathe much better, but the fungus returned with a vengeance a few months later.

    She has been on Fluconazole for 11 months total:
    (37.5mg – 75mg), and on 150mg for 3 months. 2 months into the higher dose, I found her with anisocoria (one pupil very dilated). It went away and came back over two days. One of her eyes is droopy (Horner’s syndrome). Yesterday I found blood smeared on her paw and couldn’t find a wound.

    I took her to the vet, who opened her mouth and discovered the fungal growths are pushing through her soft palate (roof of mouth) and causing anatomical separation. Her nose is swelling up considerably and distorting again. It began regressing 6 months ago but was relatively stable, but now it’s increasing in size and doubling almost overnight. She has lost 1 kilo. The vet has recommended euthanasia, unequivocally. Petra is struggling to get air in, and while we hoped for a cure (with medication) that is not happening. It’s cruel to continue with no hope of quality of life and only more suffering, and the outcome if left would be suffocation.

    We have decided to let my sweet girl go, while she is still mobile, eating, before she suffocates to death.

    It’s been so traumatic, to witness this and I want to send good vibes to anyone in the future who is struggling with the same disease (mainly the nose – which causes so much suffering).

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Kimberly | 2 years ago
I Have A 6 Year Old German Shepherd Who Has Raised Pink Lump On Her Snout. …

I have a 6 year old German shepherd who has his raised pink lump on her snout. I noticed it 2 weeks ago. I asked to a previous vet I used to work for years ago and he said apply animax ointment for a week and see if it goes down. If it goes down then okay cool , if not we need to sedate and remove it fast. I did not really want to have her sedated but I mean… I’m more curious about what it looks like and how fast it grew. It’s never happened before and it’s solid. No bleeding yet. I did forget to mention she has two. The one in her nose is different than the white one I found in her left shoulder. Is it just age ? Also , it bothered her when I touched her nose

1 Response

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  1. Krista Magnifico

    Hello,
    It is not possible to diagnose a lump or bump by a picture. This should be done with a veterinarian at an in person exam. After the exam a list of possibilities. But to truly know what it is you need cells or tissue from the mass. Like a biopsy.
    Of all the possible things it could be a histocytoma is on the list. Ask them about this.
    I hope this helps.

    Krista.

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Sandra | 2 years ago
My Year And A Half Old Great Dane Had Large Lump On Belly, Took Her To …

My year and a half old Great Dane had large lump on belly, took her to emergency vet where she put a needle in it and drained lump. Sent home with heavy duty antibiotics and pain meds. Now dog has diarrhea and trouble with her bowel mvmts. and has started puncture hole bleeding. Don’t really want to take her back to vet. Beginning to not trust any doctors as I read on your blog site that you don’t agree with draining and lumps should eventually absorb on its own. She doesn’t seem in distress or pain. What can I do to take care of her at home with giving her meds that will help her heal?

1 Response

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  1. Krista Magnifico

    Hello,
    I’m sorry but this needs to be addressed by a vet who can examine your dog. There are too many unanswered medical issues here to guess at. I don’t know what the lumps are or how they might be related to the gi issues. Or if the medications alone caused them. At minimum a thorough exam needs be done. And then an aspirate or biopsy of the masses. This may require more than one visit so it is important to find a general practitioner vet to help with the process. An er is not appropriate for this as they are often to expensive and do not have the ability to make follow up appointments to help with the long term treatment plan. For a local vet you like and trust. They can help you and your dog.

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Vivienne Barnes | 4 years ago
My Groomer Told Me Holly Has A Fungal Infection On Her Pads And To Use Apple …

My groomer told me Holly has a fungal infection on her pads and to use Apple Cider Vinegar which I did. Poor Holly nearly went crazy, I believe it stung her. Any suggestions please? Also Holly has lots of lumps everywhere which my vet says are harmless. however she has licked those on her toes and they are now raw and bleeding, suggestions please for a treatment.

2 Responses

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  1. Krista Magnifico

    Hello,
    Your groomer shouldn’t be diagnosing your pup. Please go to your vet for that and the treatment plan. We cannot, not should anyone other than your vet diagnose a health issue or recommend a treatment plan.

  2. Sarah

    I think I would check with the vet before starting anything. I am quite sure it is advice given with good intentions, but it would be smart to make sure that your vet is aware that there is an issue. They can prescribe something to help.

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William | 4 years ago
Hi There, I Wanted To Ask If Polyps In The Throat Can Be Felt. My Kitten …

Hi there, I wanted to ask if polyps in the throat can be felt. My kitten that can’t meow I suspect of having polyps. The vet tested for Leukemia and FIV negative, xrays negative, and lung worm negative. Now I notice both sides of her neck has lump, one side bigger. My other kittens do not have these lumps. My vet said she doesn’t think it’s polyps because that’s uncommon in kittens, so $500 in tests later and I have no answers. Shouldn’t they have noticed these lumps? They are the size of a small marble.

1 Response

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  1. Krista Magnifico

    Hello,
    I have only been able to feel a polyp a few times. Every so often I can do a quick enough oral exam to feel them in the back of the mouth. But even with these I needed to do a sedated exam to be sure. Kittens can get hyperthyroidism which can cause palpable enlargement of the glands on the outside throat area. This is diagnosed and confirmed with a blood test. Please call your vet to discuss these. If finances are a concern call the shelters and rescues to see if there are low cost pet care options available.

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Valerie | 5 years ago
Hi There. My Dog Ruby Had Sudden Onset Mast Cell Tumors Present About 3 Weeks Ago. She…

Hi there. My dog Ruby had sudden onset Mast Cell Tumors present about 3 weeks ago. She’s an energetic 4 year old pit/great dane mix (I know because I spent a billion dollars on a DNA kit). I noticed about 7 subcutaneous lumps on her left side while she was outside playing. They felt like little oblong marbles under her skin. Our vet is an hour away. We had moved a few months back and kept our vet because we love him so much. We still see him for routine care. There is a vet very close to our home and I have read good reviews and have had email conversation previously when I was deciding whether or not to switch vets. I was concerned Ruby would have cancer, I just felt it, and didn’t want her to have to make several long trips to our vet if she were to require surgery, etc. So I decided to take her to the new close to home vet. As it is Covid-19 season, I did not get to go inside the vet’s office with her. They aspirated one of the lumps and were concerned. She was scheduled for surgery in the following week. I talked to my other vet about this, and he was not pleased to hear they aspirated her, because he was worried that the histamines from the tumor would cause it to spread. I was alarmed and researched Dr. Google for 2 days. It seemed to me after my research that the aspiration was standard course of care. Ruby had her surgery and had 2 large masses removed. They could not take all of them because there would have been too many incision sites. Directions for care included keeping her inactive for 10-14 days, not an easy dear with an anxious 65 lb lap dog. On day 7 of recovery, I noticed a fluid buildup around the incision site. Back to Dr. Google, I decided she had a seroma. I called the vet the next morning and we took her over and my suspicion was confirmed. They told us to call if it got worse. We still haven’t received the pathology back on the two masses that were removed. This morning I decided I needed to do more research, as two new masses have cropped up (the tumors, not seroma). Ruby is in good spirits and just wants to play and run with our other dogs. She’s mad at me, I’m sure of it, for making her lay around all day. Is it normal to have a seroma after surgery? Why do these tumors pop up all of a sudden?

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Joseph | 5 years ago
Small Lump On Dogs Ear. My Dog Is Around 10 Years Old At This Point, He Is …

Small lump on dogs ear.

My dog is around 10 years old at this point, he is a King Charles spaniel x Patterdale and has never had any major health problems. He is an extremely active and energetic dog but has a small hard red lump on his ear.

I probably noticed it a few weeks ago, as far as I can tell it hasn’t changed in size. He quite often gets thorns stuck in his skin as he likes to dive into absolutely anything to retrieve his ball, so maybe it could be an infected thorn wound? Even so, I will most likely be taking him to the vet but would like some other opinions first.

(It doesn’t seem to be giving him any discomfort)

2 Responses

Comments

  1. Krista Magnifico

    Hello,
    I don’t think that you need to rush to the vets office but I do think it should be seen by them. It is utterly impossible to diagnose any limp or bump via a photo. And honestly even in person I usually have to say that the only way we know for sure what it is is with biopsy. It is small so your vet might also ok the watch and wait scenario. But if I do this with my clients I always preface it with the following:
    I measure the mass with a ruler. And I tell the client to measure it at least weekly so monitor growth. I also give a “return for recheck” instruction if it grows by 20% or more. And I further go on to say “remove if it gets ____ big”. So it doesn’t grow too big to allow surgical excision.
    I hope this helps. Let us know what happens. Also ask your vet if they think it might be a histiocytoma. I’ve seen lots of them. Good luck.

    1. Joseph Post author

      Hi, thanks for the advice!
      As I haven’t noticed much (if any) growth, I’ll give it about a week or so to see if it does grow or shrink. And if it stays the same or increases in size I will take him to the vet. Like you said, it’s very difficult to tell what it it just by a photo or without a biopsy, but I did do some googling and it does look similar in appearance to a Histiocytoma. Even so, he will most likely go to the vet.

      Thanks for the advice!

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Morghan | 5 years ago
Need Help!! My 9 Year Old Dog Has Had A Lump On The Side Of His Face …

Need help!!
My 9 year old dog has had a lump on the side of his face which looks like a cyst for a couple of years now. It didn’t look serious and he appeared fine so we never took him to a vet. Now we are getting worried as it keeps getting bigger and now appears a reddish colour and appears to be bleeding slightly. We are going to be taking him to a vet but I also would like some opinions before I go there.
In the image I have put in below is the lumps current state.
If u could please give what a normal procedure would be to treat it and estimated price(UK) that would be greatly appreciated

2 Responses

Comments

  1. Krista Magnifico

    Hello,
    It is not possible for anyone to diagnose via a photo. Please bring your pup to the vet as soon as possible. I am very worrie this is going to rupture and it will not stop bleeding as it is not normal tissue. I am concerned it might be some kind of cancerous lesion but I also hope and believe ( based on how slow growing it is ) that is is not a malignant or aggressive kind. Please see a vet and have it removed. It looks like this can be done without too much difficulty. I wouldn’t waste time or money on aspirates. If you are on a tight budget find someone who will remove it before it becomes a bigger problem. Please let us know what happens. And best of luck.

    1. Morghan Post author

      Thanks so much for the opinion. We are taking him to a vet ASAP. I hope he will be ok. Will keep u updated about it.

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