Hello all,
Writing in with an agonizing and drawn out struggle with my cat Petra..

I rescued a feral kitten in 2022 who developed cryptococcosis the following year – confirmed through a biopsy.
She has the cutaneous and nasal form, and while we tried itraconazole for a few months, it did devastating damage to her nose.
Vet switched her to fluconazole 37.5 mg (at that time my cat was just over year old and weighed 3.5 kg) once a day… and the symptom relief was remarkable!
Within a month, her nose was much less inflamed and starting to look “relatively normal” again, and best part was she was no longer having difficulty breathing, no stertor or mouth open.
Her many crusty skin lesions and nodules under the skin cleared up miraculously!

But, the success was short-lived, because a couple of months later she developed a big bulge on her abdomen/side under the skin – which eventually erupted. She had had several of these nodules and lumps, that ulcerated last year but the fluconazole seemed to clear them all up. Until now. I was so disheartened, to say the least.
The crater-like ulcer got infected and our vet (RCVS licensed in UK) decided surgery was the best option.
We did this, and the vet found more ulcers which needed to be removed to patch up the skin. It was a horrific looking surgery aftermath when she came home.

Petra required to wear a cone for 3 weeks after her surgery so she couldn’t touch her healing wound. It got infected anyway, and this increased her “cone suffering” duration.
The impact of many vet visits, surgery, and follow ups while the vet checked if the wound was healing and if the stitches could be removed, was quite an ordeal for Petra.
She gets very stressed and is difficult to put in a carrier. I feel that the stress of cone duration + all the vet trips triggered an inflammatory response in her and her nose started showing signs of the fungus again. Inflammation, distortion and worst of all the stertor was back.

The vet increased her fluconazole dose to 75 mg a day (37.5 mg morning, 37.5 mg evening). This had no noticeable effect and her nose got more inflamed as each day went by. 2 months later and her nose is worse than ever and the tip is so inflamed. With the loss of scent and ability to breathe sufficiently, she’s become reluctant to eat more than half a tin of food a day. Sometimes all she will eat is half a tablespoon and then runs off, upset.

Petra’s vet wants to put her on a maximum dose of 150 mg of fluconazole, daily, before assessing her quality of life and potential euthanasia.
I decided to try homeopathic remedies first, while continuing 75 mg a day of fluconazole) but it doesn’t appear to be helping 3 weeks in.

I’m concerned about continuing vet interventions, because Petra is so stressed by them, and at 150 mg a day she will need to see the vet frequently and likely need blood tests. At 150 mg a day, it’s also a non sustainable chunk of my monthly expenses (taken from diminishing savings), and she is not my only cat or responsibility… this could go on for years..

If she has no positive response (symptoms relief) at 150 mg, the vet is out of ideas other than euthanasia. I live in Bahrain and the options for treating this fungus are very limited.
They have not seen it in over 40 years of vet practice, so this is a first time.

I love Petra and it’s been hell witnessing her struggle to breathe for over a year. That’s what makes me panicky and consider quality of life, if she cannot be cured or brought to a level of management where the fungus doesn’t impede her breathing.

I need advice from a community of animal lovers, vets, who can also understand and take into consideration her temperament and adverse reaction (inflammation) to vet visits.

I was really hoping the homeopathic medicine would help and the practitioner I found has many years of successes working with animals. It’s either the wrong remedy, or just going to take a long time. In the meantime, in my opinion, my cat is suffering and struggling. She takes gasps of air every so often and her mouth is slightly open while she makes a snoring sound as she tries to breathe through her blocked airway. She has lost weight as she eats much less now. She was 4.7 kg in April before her surgery. At the beginning of June she was 4.5 kg and now she is closer to 4 kg.
Also within the last 2 months, her eyes have gotten affected by the nodules. One above her right eye, under the skin and affecting the bone. The other is in her left lower eyelid.
During this whole ordeal, her right lymph node under her jaw has been the size of a golf ball.. and the left one also swelled up a few months later. But that side seems to have gone down.

Any help or advice on what to do.. would be very much appreciated.

Pics from most recent (today June 3rd 2024) to last year before fluconazole and way before, late 2022, when she was a kitten.

Hello,

I called Jarrettsville Veterinary Center this evening and they told me I should reach out on Pawbly with my question. Around the beginning of the year, I noticed my cat’s eye started to look a little different. I was seeing some discharge and it looked like it could be slightly infected. I wasn’t really worried about it and thought some type of drop would clear it right up. It did not get better and actually got a lot worse. It’s been months of appointments, different treatments and multiple drops to try and fix it. Where we are now is that she’s been going to an ophthalmologist for the past month who has diagnosed it as a corneal ulcer with entropion on her lower eye lid. The ophthalmologist is recommending surgery to correct the entropion and to do a debridement on the ulcer at the same time. I immediately started researching because the price I was quoted for the surgery is something that would be incredibly outside of what my husband and I can afford. I came across Jarrettsville and saw the prices are posted online which was incredibly helpful. I completely understand those are estimates and there are other factors that would contribute to the final bill, but Jarrettsville would be way more on par with what we can afford. I was so unbelievably excited when I found this place!

Also, I would be coming from Philadelphia (about 1.5 hours away) but would have no problem driving all that way if this surgery can be done by you. My question is though, since she’s been seeing an ophthalmologist already here and I’ve been told what needs to be done, if I were to send all of those medical records and also get pre-operation bloodwork done at our primary vet here, and sent that all to you, would that be sufficient in place of a pre-operation consult visit? Since we are so far away? If not, that is TOTALLY okay and I’d be willing to make the drive as many times as necessary for my cat. I just thought I’d ask.

I really appreciate any help you can provide. We are in a bit of a desperate situation. I don’t want my cat to suffer but we really just cannot afford the price we were quoted. I hope to hear from you soon and thank you so much in advance!

Becky

My cat seems to have an ulcer on his neck, this is the second one he’s had the first was on his shoulder blade it’s clean and there’s no hair around he’s eaten today but it worries me, he doesn’t seem to be in pain or even notice it but it’s gooey and smells odd should I rush him to the vet?

Species: Dog

Age: 4

Sex/Neuter status: Not neutered

Breed: Weimaraner

Body weight: 66lbs

History: He started showing sings of what appeared to be the mange at 3 y-o. Before this he was completely healthy and hadn’t had any sorts of trouble or illnesses. He was taken to 4-5 different vets and he had some studies done where they determined he had staphylococcus aureus on his skin. Most of them agreed that it was mange and suggested the following treatments (at different times, to no avail):

* Inyected clindamycin
* Ciprofloxacin tablets
* Cephalosporin (don’t know if tablets or capsules)
* Omega 3 and 6
* B complex and casein shots
* Shampoo with amitraz
* Florfenicol .6% spray
* Aluspray
* Antisebhorreic shampoo

And he is currently on an hypoallergenic salmon diet with special food.

Clinical signs:

* Weight loss
* Very swollen paws and skin in general
* Hair loss
* Loss of appetite
* Ulcers
* Lethargic
* Some fever here and there
* Redness in his eyes

Here are some pictures of him http://imgur.com/a/FgYiT

This is him a couple of months after it started a year ago http://i.imgur.com/whXOmQs.jpg

Duration: 1 year

Your general location: Mexico city

What could this be? What can we do for him? We’ve tried everything and it seems like nothing works and we’re scared to death. We want him to get better.